Chronic Fatigue Syndrome

Chronic fatigue syndrome (CFS) is a debilitating disorder marked by profound and persistent fatigue that is unrelated to physical exertion and cannot be relieved with bed rest. The long list of accompanying symptoms includes weakness, muscle and joint pain, headache, insomnia, anxiety, depression, indigestion, and impaired memory and cognition. Sometimes called myalgic encephalomyelitis (ME), postviral fatigue syndrome (PVFS), or X-associated neuroimmune disease, CFS afflicts 1 to 4 million Americans.

Causes of Chronic Fatigue Syndrome (CFS)

Chronic fatigue syndrome (CFS) has no known cause and is difficult to diagnose. Researchers recently discovered significantly high rates of viral infection among people diagnosed with CFS. Confirmed association with the xenotropic murine leukemia virus-related virus (XMRV), previously associated with prostrate cancer, may open a new era of CFS research, diagnosis, and treatment.

Treatment of Chronic Fatigue Syndrome (CFS)
with Hyperbaric Oxygen Therapy

Many physicians and patients have reported temporary relief from primary symptoms of chronic fatigue syndrome (CFS) immediately after hyperbaric oxygen therapy (HBOT). In limited studies HBOT has also been shown to relieve general fatigue and to reduce the pain associated with fibromyalgia and other chronic pain disorders whose symptoms sometimes resemble CFS. Physicians may prescribe hyperbaric oxygen as an adjunct or alternative to drug treatments and other therapies.

HyperbaricLink Evidence Index for Chronic Fatigue Syndrome

HyperbaricLink Evidence Index
2 citations
0 appraisals
0 trials

The HyperbaricLink Evidence Index is our at-a-glance summary of the clinical evidence on HBOT for the treatment of specific diseases and conditions. Scoring is based solely on our reading and interpretation of the medical literature.

  • Disproved - Strong evidence against using HBOT.
  • None - Unfavorable results or no published evidence.
  • Scant - Early or mixed results with lingering questions.
  • Promising - Repeatedly favorable results urging further study.
  • Compelling - Strong body of evidence meriting approval.
  • Approved - HBOT indicated and widely reimbursed.

Follow the links to our primary sources to read the papers and analyses that have shaped our views. lists most all scientific papers published in reputable medical journals. critically appraises key studies in the hyperbaric medical literature. lists human clinical trials currently enrolling, in progress, and recently completed.


More information on Chronic Fatigue Syndrome (CFS)

NOT APPROVED indication for HBOT by UHMS
Google Scholar

HBOT news about Chronic Fatigue Syndrome (CFS)

More news from O2.0 – the HyperbaricLink blog

Complete chronic fatigue syndrome news archive from O2.0 — the HyperbaricLink blog.

Chronic Fatigue Syndrome, MedlinePlus, US National Library of Medicine. Retrieved 10 May 2011.
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Updated: 02 May 2015 12:00 AM
Created: 06 Nov 2009 12:00 AM
By: About the authors »